Please keep me posted. Like so many mysterious events in medicine a treatment may work here but not there.

🙏🏻

I have had Pyoderma Gangrenosum twice. The first instance was on my left thigh. My dermatologist tried everything she could think of but after a biopsy showed the ulcer was PG I was referred to the Wound Treatment Clinic. We tried many salves, lotions, bandages, whatever they could but it continues to worsen until my oncologist put me in chemo . He had been treating me for CLL. It was Rituxin and Bendimustin. At the same time the Wound Clinic began using skin grafts from donated placenta tissue. The chemo and skin grafts finally closed the wound. It left me with a large scar in my thigh but it healed. That was 6 years ago .
In May of this year a small pimple appeared on my face and within days it grew larger. I immediately saw my dermatologist who again diagnosed PG and injected the area with Kenalog and referred me back to my new oncologist. It was only after my dermatologist spoke with my oncologist that she agreed to infusions of Rituxin. Fortunately the PG was caught in time and treated promptly so I am only left with a smallish purple scar on my face.
I am now left with a third hematology oncologist who does not seem to believe PG can be related to an immune issue and said he would approach any further outbreaks of PG as something to be treated by a dermatologist. Meanwhile my Absolute Abnormal Lymphocyte count went thru the roof. There is so little information available on PG and so few doctors with any understanding of the condition it seems we must somehow insist on being treated by a combination of a dermatology and oncology regimen. Extremely frustrating and frightening .
First pic is part way thru treatment on leg .
Second pic is small pimple on my face as PG began.
Third pic is scar remaining on my leg after chemo and skin grafts .