Hello @valx , so sorry this is happening to you both. Cancer diagnosis and treatment plus anxiety issues is a tough combination. I had radiation plus a targeted therapy for 7 weeks after my surgery in 2012. It is a tough time, but survivable knowing there is an end in sight. Keep an eye on the light at the end of the tunnel. Nausea and inability to eat due to changes in the taste of food and pain in the mouth from radiation make nutrition hard to attain. With his achalasia, I would think a feeding tube would be a huge help and I would request it if it were me. Total exhaustion is very real and you have to listen to your body when you need rest. That said, keeping up with whatever exercise you can accomplish will keep your strength up. Maybe it's a 10 minute walk down the street, but it will help and getting outside helps your attitude also. He needs to dig down deep and find a positive attitude that he can beat this thing. With great doctors and all the new immunotherapies, etc his odds get better by the day. Books I have read that helped build hope: How Not to be My Patient by Ed Creagan MD, a palliative care doctor at Mayo Rochester. You can buy it via their bookstore or on Amazon. I also appreciated Radical Remissions by Kelly A Turner. She also wrote Radical Hope along the same lines. Join the head and neck support group SPOHNC as they have recipe books and good information for managing Radiation and chemo effects. Get him to use Connect if you can, it is such good support. My husband was not always a good patient during his cancer journey either and I am convinced that the caregiver role is tougher than the patient role many times. It is so hard to know what they are going through, and to see them in pain and depressed. Be supportive when you can and also take time out for yourself to stay healthy amidst all this stress. This is a marathon and not a sprint, but there is a finish line ahead to be his first goal. Hugs and best of luck to you both.