← Return to Looking to connect with people who have non-diabetic neuropathy

Discussion
Comment receiving replies
@johnbishop

Hi @usveteran, Welcome to Connect. I'm not sure if the article you were looking for is one of these but they are on the same topic and may be helpful.

--- How can proton pump inhibitors damage central and peripheral nervous systems?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716020/
--- Drug-Induced Peripheral Neuropathy: A Narrative Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365998/.

There is another discussion on the topic where you can learn what others have shared on the topic here:
--- Neuropathy + Proton-pump Inhibitor use?? Anyone had this experience?: https://connect.mayoclinic.org/discussion/neuropathy-and-ppi-use-has-anyone-had-this-experience/.

Is it only the one toe with the pain symptoms? Do you think it something other than neuropathy?

Jump to this post


Replies to "Hi @usveteran, Welcome to Connect. I'm not sure if the article you were looking for is..."

Drug-Induced Peripheral Neuropathy: A Narrative Review ---- I believe this was the article I had read earlier during a google search about the OMEPRAZOLE I had been taking. The discussion of "AZOLES" was the last medication described in the documentation as I had remembered. Thank you for noting that - it is an excellent technical presentation concerning the neuropathy side effects of multiple drug compounds. _____ The only pain affected member is a single toe, and specifically the tip edge surface in front of the toenail is also touch sensitive. The symptoms are irritation as in burning, throbing, jabbing, and tingling. Massage and handling brings temporary relief for a few minutes or so. I requested Gabapentin up to 600mg /day, and found that food ingestion typically blocks the effectiveness. I likely have drug induced PN from the Omeprazole that the said article proposes is more likely in patients pre-disposed to PN or diabetes mellitus - which I may have a borderline mellitus (red skin spots) condition thereof.