I am on my fourth year of being on anastrozole. No horrible side effects for me. Still get hot flashes. My body temperature regulation seems askew. So, I am in charge of the thermostat and fan controls LOL. Dry EVERYWHERE 😉. My skin got “grandmother-type” wrinkly within 3 months of starting the drug. And the occasional pimple on my face turned into an actual case of acne, which I now have a prescription of Retin-A for. My hair... it definitely has affected it. It is quite thin but I’ve not lost coverage.