I started on 40 mg of prednisone -- my inflammation was a 69 -- I have been on 40 since late February and taking 10Mg of Methotrexate for 2 months -- My appointment with a Rheumatologist is June 21, so my family doctor has been trying his best -- We tried to cut the prednisone down to 20 but within a week the pain and immobility was back - even on 40mg my monthly labs still have my inflammation at 63 -