@k13 , It's all kind of a blur now (13 months since I stopped Folfirinox after 12 biweekly treatments, and 4.5 months / 10 rounds since starting the biweekly Gemcitabine + Abraxane + Cisplatin).

I think they're about the same in terms of overall impact on me. I probably felt crappier on the Folfirinox, but for shorter periods of time (2-3 days) than with GAC (3-4 days). Fatigue and digestive issues (reflux, metallic taste) have been common with me in both, but Abraxane added the near-instant hair loss.

My local oncologist thought the 3-drug combo (GAC) would be especially nasty with the addition of Cisplatin, but I'm receiving the chemo at a different center, and maybe the pre-med recipe is better there.

I've been pretty lucky / blessed with both to gain & maintain my weight & appetite for at least 10 good days out of 14. 🙂