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Decipher Results are in... ADT recommendations?

Prostate Cancer | Last Active: Jun 26, 2023 | Replies (10)

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@dgd1953

69 years old with two of twelve cores at 30% Gleason 3+4. Decipher was very high. PSMA PET scan indicated the cancer is confined to the prostate. Opted for IMRT which starts tomorrow. Initially my urologist said he would be giving me ADT injections, but my RO was adamant that I did not need ADT. His thinking was that the small survival difference ADT would make was not worth the associated negative quality of life. He also pointed out the dangerous health issues that can be associated with testosterone blocking (cardiovascular in particular). His position is that my cancer is “low grade” and can be cured by radiation alone. The urologist and RO put their minds together and now the urologist agrees that ADT is unnecessary. I’m happy not to be taking ADT and hoping the docs are right. Time will tell.

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Replies to "69 years old with two of twelve cores at 30% Gleason 3+4. Decipher was very high...."

Had it not been for the Decipher results, I probably would have passed on the ADT in spite of my single 4+3. From my research, I believe that tests such as my Decipher test will be a major factor in future ADT recommendations. There's a large ongoing NIH study looking at that particular subject now. Best wishes!