Sparklegram, I was on Anastrozole for about 6 months and had some awful side effects. The worst being problems with cognitive function and memory loss. I was very fearful that I was starting to slip into dementia. My doctor switched me to Tomoxifin and the cognitive problems were better, but not relieved. She then gave me several months of no meds at all to see if those cognitive issues world get better. Sure enough, after just a month or so of being off meds., my cognitive abilities were fine again. Yes, Anastrozole and other estrogen medications can cause memory issues. At my most recent appointment, about a month ago, my oncologist switched me to Exemestane. So far it’s been ok, with few side effects. Hoping it stays that way for me! Best of luck to you in finding just the right treatment/meds for you. I surely is a challenge!