This is just slightly off topic but I had to share...........I had Stage 1 Lobular BC, no lymph node involvement and low risk of recurrence BUT I wanted to try the AI's and tried them all. I couldn't tolerate any of them due to the usual side effects and some relatively serious. I had my hormone levels checked by my oncologist multiple times and my levels of Estrogen were low (ER positive BC for me). Here's the next saga......I have been having some vaginal atrophy over the past few years and it finally became so bad that I had to start using vaginal estrogen. I have worked so hard to reduce my estrogen so my breast cancer won't recur (a goal we all share in a big way) and although this cream is low dose and doing the trick for me, I'm feeling all sorry for myself because it seems the hormone woes just never end. Sigh.....