Hi,
I did 12 rounds of Folferinox, one week on and following week off, for my stage 1 PC. CT scan showed cancer cells had invaded my liver and elevated CA 9-19 as well. So, Folferinox failed in stopping metastatic disease. I was switched to the Gemzar/Abraxane regimen, three weeks on and one week off. The fatigue is definitely more pronounced with this new regimen, and I begged off for the fifth treatment because I didn't feel up to it. The side effects have been cumulative for me, because the initial treatments seemed ok, and I felt ready for the next one, until number five. I only had to have one Folferinox treatment cancelled because of feeling more unwell than usual. Everyone reacts differently, but I hope my experience is helpful.