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Kevzara (sarilumab) to treat PMR

Polymyalgia Rheumatica (PMR) | Last Active: Aug 24 6:34am | Replies (162)

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@sandiw77

Hi @sheralee, I have just started taking Kevzara and really don’t have any thoughts yet. I just took my 2nd dose this morning. It’s only administered once every 2 weeks so I’m just hopeful that side effect free change is coming! 😂🤣 Will let you know when I have a true observation. Blessings!
Sandi

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Replies to "Hi @sheralee, I have just started taking Kevzara and really don’t have any thoughts yet. I..."

I hope you have good luck with Kevzara. I'm on Actemra which my rheumatologist wanted me to try 4 years ago to treat refractory PMR. Actemra works well for me. I look forward to hearing about the experiences other people have with Kevzara.

My experience with Actemra has been positive. I was able to taper off prednisone in less than a year after Actemra was started. I might have some minor sided effects from Actemra but nothing compared to all of the problems prednisone was causing. Prednisone relieves pain faster but in the long term, my rheumatologist thinks I will do better on Actemra.

Kevzara and Actemra target the same IL-6 inflammation pathway that is implicated in both PMR and GCA. Kevzara is FDA approved for PMR. Actemra is FDA approved for GCA. To the extent that PMR and GCA are "associated" I think either biologic might work for both conditions.