@francine6829 Unfortunately, I have a family history of blood clots and so Tamoxifen will be a last choice if I fail the aromatase inhibitors. In addition, the second tumor I have is a more aggressive type of cancer for which AIs would handle best. I'm very happy that you are doing well with the Tamoxifen and wish you all the best.

I have been on Anastrozole which caused severe memory/cognitive issues, along with the aches and pains. Then my doctor put me on Tomoxifin, that was better but some brain fog continued. It seems I can choose between the possibility of cancer returning, or not being able to think clearly.

@francine6829 Hi Francine, How long have you been on Tomoxifen and what dosage. Thanks

Francine6829, sooooo pleased for you that Tomoxifin is working!!! I was on Tomoxifin for a few months and the side effects were better than when I was on Anastrozole, but I still had some nasty side effects. My oncologist has let me be on a break from meds for a few months as my cancer was a very slow growing type. It’s been heaven to have the break!! But I’m supposed to go back on Tomoxifin when I see her at my next appointment in late September. Not looking forward to it!