Thank you for this advice. Unfortunately my husband plans to go through with his current biopsy (rectal) because he is too anxious about delaying the procedure while he finds another doctor willing to do the perineum approach. He lost his mom 3 years ago in a matter of a few weeks from a very aggressive form of cancer so his anxiety level is unfortunately quite high. We will have to say lots of prayers that things go well. Once the biopsy is complete, then we do plan on switching his care over to Mayo, regardless of the outcome of the biopsy, for either continued observation or treatment if cancer is found. Thank you so much for your guidance.