I chimed in here in early spring of 2022 when I had multiple biopsies of angry spots on my shins followed by two Moh’s surgeries. When the Moh’s surgeries had healed, my dermatologist ordered 4 to 6 weeks of Flourouricil ointment, which I call do-it-yourself chemo. I did it for 5 weeks until I couldn’t stand it any more. My skin turned an angry red from knees to ankles. The worst spots burned and itched and scabbed until eventually a layer of skin came off. Same doctor then gave me a prescription for two weeks of a steroid cream to “calm” my legs. After that she suggested a daily regimen of CeraVe over-the-counter cream to moisturize. I meekly asked if I could try on my legs two products that I have long used with success to fade brown spots on my face: Tretinoin creme (a prescription) and Amlactin lotion (over-the-counter). Best prices on both are at Costco. She shrugged and said I could try them if I wanted to. She gave me an Rx for a new tube of Tretinoin every 3-4 weeks. Well, the results have been amazing! I just had a six-month checkup, and the doctor found NO spots that she wanted to biopsy. A very few spots may continue to scab, but when those scabs fall off, there is beautiful new skin beneath them. I use the Amlactin all over my body after a morning shower, and I rub the Tretinoin creme from my knees to my ankles every night at bedtime. On any morning that I don’t shower, I slather Cerave on both legs. And I wear compression knee-high socks all day to improve circulation. The results were not instant. I started this regimen last November 1st, and it took at least four months before the skin on my legs began to look better. I may continue this regimen forever.