I concur with letting a professional disconnect the pump and flush the port. Maybe your insurance can send a home health nurse to do that.

I did Folfirinox for 6 months, with the at-home pump for 46 hours. For sleeping, I wore the strap over my neck with the pump over my upper abdomen. I work a "rash guard" (surfer's skin-tight, breathable lycra shirt) over the pump to hold it in place, since I toss and turn between sides when I sleep. Very helpful. You could do something similar with backpack straps, ace bandages, sports bra, etc...

As far as alternate treatments go, there are numerous clinical trials, but challenging to find the right one. As mentioned before, check with PanCan and Cancer Commons, and also with other major medical centers near you.

If there's nothing appropriate near you, some of the trial sponsors will pay for transportation and lodging. The biggest centers typically have the most trials, but local-centric oncologists are often not aware of them. You could always contact the trial coordinators at Mayo, Anderson, Farber, Langone, Sloan Kettering directly.

There's one treatment that's in various trials, including a few related to pancreas cancer, that is basically free of side effects, called Tumor Treatment Fields. You wear a backpack and a couple antenna patches that transmit an electric field through your body to disrupt the tumor cell reproduction. I think it has only been studied in conjunction with other standard-of-care regimens, but it seems like an ideal alternative to study in patients who can't tolerate chemo/immunotherapy regimens.

My 85-year old dad with mesothelioma had to stop his immunotherapy in January, and has declined to try any other drug-based therapies. I keep hoping his oncologists can work out something with the TTF equipment manufacturer on a compassionate-use basis, but they don't seem willing to take on the additional paperwork.

Mayo has an open trial with the TTF equipment for pancreatic cancer, but the participation criteria are rather specific; I think you have to have visible mets on the liver, and have not been treated with gem/abrax/cisplatin before.

If you do a wider search for "Tumor Treatment Fields" and manufacturer Novocure you might be able to get in contact with more researchers who know something about it.

I hope the meeting with your oncologist went well, and wish you the best.