Starting hormone treatment for prostate cancer: How did it go for you?

hormone is easy and painless and it works wonders I was on it for 13 months with Erleada and I had a good outcome for my aggressive CR gleason 9 PC Good luck

I'm on Eligard and Zytiga for 8 months and psa is undetectable.

I received a total of 3 shots, Firmagon and Eligard. The first two, Firmagon went ok, however the 24 knockdown of my testosterone was a bitch. Other than that I did well and proceeded to High dose Proton radiation. That was three weeks ago today. Dealing with some radiation side effects, but handled the shots well. Just waiting now for things to return to normal, if that’s possible after cancer and treatments.

My brother is on Lupron and did the MRIdian viewray radiation in NY at Cornell Weil/Presbyterian last January. He described the side effects as annoying and is looking for a way to take fewer Lupron treatments. His PSA is now .12.

I have regional metastatic PC, Been on Eligard for the last nine months and Zytiga the first six months. Testosterone and PSA were undetectable after 3 months. My last MRI/CT scan Last January couldn't find any cancer, the term was grossly undetectable every where. I went back and forth on getting IMRT. I was wondering what they were going to radiate if it was undetectable? And how would they know if they got it all? I didn't care for the answer I got from my RAD Therapist. So I decided to have laproscopic , endoscopic, Radical PE next month. Thinking I would rather have them take out everything. If it comes back then they will have something to radiate.

Good luck Pianoman. That would be my thinking too!

A quick follow-up on this topic as I realize my input above was brief.

I was 42 when I had prostate cancer and had my prostate removed and 52 when my cancer returned and as mentioned above I am on Eligard/Zytiga and my PSA is at undetectable levels and my doctor does not suggest any other treatments currently. My current treatment could continue to deliver an undetectable PSA for many months, or many years, but eventually my metastatic hormone sensitive prostate cancer (MHSPCa) will become hormone resistant (MHSPCa) and the current treatment will lose its efficacy. I do have a BRCA2 mutation, however, while BRCA2 mutations do predict a shorter time to becoming castrate resistance, that isn’t always the case, and my doctor has several patients who have lengthy times of sensitivity to ADT combinations such as mine.

When that time comes, a variety of therapeutic options will be available. One such option is a PARP inhibitor such as Olaparib with an Androgen receptor signaling inhibitor such as Enzalutamide. The next option will be utilizing a platinum-based chemotherapy regimen such as Docetaxel and Carboplatinum. Last but not least, an option that is only approved by insurance if the other options have been exhausted is theranostic nuclear medicine such as Pluvicto. All of these have side effects of increasing impact.

I hope this helps.

What was your PSA when you started hormone therapy ?

19.8

I took the 6 month shot. Side effect are bad. Still haven't got my testosterone back after 18 months with no explanation from my doctor.