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Concerned about the side effects of anastrozole
Breast Cancer | Last Active: 5 days ago | Replies (1931)Comment receiving replies
As posted a few days ago, I would encourage you to read the meta-analysis on aromatase inhibitors versus tamoxifen which I believe addresses some of your questions. https://www.sciencedirect.com/science/article/pii/S0140673615610741
Replies to "@farmgirl1556 @francine6829 As posted a few days ago, I would encourage you to read the meta-analysis..."
Wow! This study is really interesting. Summation: Interpretation
Aromatase inhibitors reduce recurrence rates by about 30% (proportionately) compared with tamoxifen while treatments differ, but not thereafter. 5 years of an aromatase inhibitor reduces 10-year breast cancer mortality rates by about 15% compared with 5 years of tamoxifen, hence by about 40% (proportionately) compared with no endocrine treatment.
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I would love to see this test with a placebo included in the mix, rather than a simple comparison of two drugs. Also - age specific results. It still doesn’t answer the question of age specific morbidity stats for Stage 1 with radiation OR radiation+AI OR radiation+placebo … THAT is a study that would give answers to me and many others. If anyone finds that study, you will become my new best friend (lucky you).