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Concerned about the side effects of anastrozole
Breast Cancer | Last Active: Nov 21 7:48am | Replies (1935)Comment receiving replies
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874410/
Samy - You got me curious about this..........I'm not sure the link above will work. I'm not very good at links and such but this is an article on the NCBI-NIH (National Institutes of Health) website.
I looked at several articles. They are written in medical language and it takes a while to plow through them but...this one references 'older breast cancer patients' and treatment options, including AI's. There are several studies listed on the difference between Lobular and Ductal and AI effectiveness and 'the older' patient .........I think we're all 'older', ha ha....but it does address some of our concerns.
If you can't get to the article, Google or Websearch, effectiveness of AI's in early stage or Stage 1 cancer. I found lots of studies.
The upshot I got was this...........the AI's work but side effects and compliance by older patients are a strong consideration and Lobular really is different than Ductal and is just now being treated as such.
Hugs...........
Replies to "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874410/ Samy - You got me curious about this..........I'm not sure the link above will work...."
This is very interesting article - but written in 2013. I wonder if they have any more recent data - I'll ask my oncologist. But I don't see her until July.
That article about "Early breast cancer in the older woman" is a good find, @cindylb. Note that it is from 2012, @samy, but it is a great place to start making lists of questions for your oncologist. I did some digging around as well and found these 2017 articles.
- Aromatase inhibitors for early-stage breast cancer https://www.ncbi.nlm.nih.gov/books/NBK447104/
- Aromatase inhibitors in the extended treatment of early-stage breast cancer https://www.ncbi.nlm.nih.gov/books/NBK447116/
- Aromatase inhibitors as upfront therapy for early-stage breast cancer https://www.ncbi.nlm.nih.gov/books/NBK447121/
@monical, you raise some valid concerns. When your doctor prescribed anastrozole for you, did you have time to tell her about your concerns or are they coming up now as you learn more about possible side effects? Maybe it would be a good idea to schedule an appointment to get your concerns addressed before starting.
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THANK you for that article. It’s the closest to answering my question. It would seem that radiation OR radiation+AI drug doesn’t produce a significant difference mortality. Although this is only one person’s opinion, it doesn’t surprise me. I’ll read it several times, to understand as well as I can … and keep searching for more ino. Bottom line is, I guess, I need some serious convincing that this poisonous drug will be worth it for someone my age…so far, I am NOT convinced. The “lump” I had was never felt, by me or doctor, mammogram found it and subsequent tests confirmed. 1.6cm very deep.