samy - VERY good questions. I am on my second AI (Aromosin) and starting the feel the aches and pains (not as bad as Femura), but still. Have you asked your oncologist if you could go on Tamoxifen? Yes, I know this is a first generation drug, and primarily for pre-menopausal women, HOWEVER, i know postmenapausal women who used it and did not experience side effects. I would like to the reoccurence rates for Tamoxifen vs the new AI drugs?