@samy,- Samy, I definitely understand your indecision and hesitation about taking an AI drug. You are only 69, though, and to me, that's YOUNG! I'm nearly 75. I have a husband, daughter, son-in-law, and two beautiful young grandchildren. I tutor children during the week. I don't want to take the chance of having a recurring bout of cancer that could possibly take my life away. I've been on Arimidex for 15 months and I have good days and not so good days with the side effects. It seems from this forum that most of the AIs have similar side effects. I guess we all have to decide how we're going to tackle this and I hope some day, a better medicine will be discovered. For now, though, I have to choose staying on the ones that are now available to us. I truly do understand your quandary, though. I hope you stay with this forum, though. It is a comfort!