I had not heard of this, and the link you provided was interesting, so I jumped to my go-to source Google Scholar, and found this extensive 2020 article from the NIH - National Library of Medicine - originally from Biotechnology Reports, a self-publishing journal. Most of the authors are affiliated with the pharmaceutical company which manufactures the product.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585045/
I found a lot of other articles too which talked about anti-inflammatory effects of the enzyme, potential anti-mucolytic effects, and possible anti-biofilm properties. There are also cautions regarding use with blood thinners, NSAIDs, asthma, etc.

So as with all supplements, be sure to check with (all) health care providers before starting, and buy from a reputable source.
Sue

@sadair20
Yes. For me it works like aspirin for migraines but without any of the side effects. It used to be prescribed to reduce oral inflammation. It was made from silkworm bacteria, but now is produced from algae. It's been around a long time, first as prescription only. I think it might be underrated as a safer anti-inflammatory than popular NSAIDS, probably because research results have not been steller (it might have a mild effect) and there is no money in it. It is worth trying in place of NSAIDS. and best if taken on an empty stomach.