I worked during my 6 months of Folfirinox (age 58-59), then took 6 weeks of leave after the Whipple, went back half time for a month, then full time again. After recurrence and new chemo, I'm still working full-time, except for the chemo days.

I was getting the biweekly Folfirinox at a center close to home, but since Day 1 was all day, that was a full day off work every time. Since that regimen included 46 more hours with the take-home pump, the next two days had to be work from home. I would generally make Day 1 a Wednesday, so Thu/Fri were at home, recover over the weekend, and resume work (mix of at-home and in-office) on Monday.

With the new regimen (biweekly Abraxane + Gemcitabine + Cisplatin), it's all done in one day, but I chose to do it at a center 2.5 hours away, so there's 5 hours of driving on top of 5 hours of chemo. I generally do those on a Friday, recover on the weekend, and work from home Monday if possible. I'm wiped out every other Saturday, and my ninth treatment last week really knocked me for a loop all week. I found out some of the vitamins and herbs I was taking were not recommended during my chemo, and stopping those may have contributed to the fatigue.

None of it has been easy. My boss understands that midday naps are sometimes necessary, and I'm consuming a lot more caffeine than I should to get through each day. I still walk 2 miles every night and then cool off with a shower before bed to help get the caffeine out of my system.