The sleep issue is one reason why doctors tell us to take prednisone in the morning. Prednisone can also upset your stomach so taking it with breakfast is a good idea. Taking prednisone in the morning with breakfast means it's less likely to affect your sleep and upset your stomach.

When I was able to sleep through the night without pain, I switched to taking prednisone all in the morning with breakfast. When I could go an entire 24 hours on a single a.m. dose, I felt like things were improving.

I don't expect to be completely pain free. I don't take prednisone anymore but I still have pain. I have arthritis and other things that are causing the pain so knowing that makes it easier to cope with the pain. The pain is tolerable now. The pain and stiffness of PMR was not easy to tolerate. The pain seemed like it happened for no reason at all.