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@whineboy

It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the past four years. For the ~ 15 years before that, it ran 42-51 mg/dl.

What changed? I lost 55 lbs on a low-carb diet combined with daily exercise. And I have kept it all off without any backsliding. And my rosuvastatin dose has been halved.

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Replies to "It most certainly was possible for me. My HDL has been between 75-82 mg/dl for the..."

Wow - great job changing your lifestyle!

Here are a few articles with mention of extremely high HDL ... I can't interpret this, but your HDL seems incredibly high based on my limited knowledge. At least one of the articles refers to a Danish study that indicated lowest mortality in men of an average of 73 - so, you're right there. Other articles infer you are pretty high and should review other factors. Again, I'm not qualified to comment further.
https://my.clevelandclinic.org/health/articles/24395-hdl-cholesterol#:~:text=An%20elevated%2C%20or%20abnormally%20high,trouble%20getting%20rid%20of%20it.
https://www.webmd.com/cholesterol-management/good-cholesterol-too-high
https://www.uspharmacist.com/article/common-otc-drugs-supplements-potentially-can-confound-laboratory-results-1-1
https://www.heartuk.org.uk/genetic-conditions/high-hdl-cholesterol
https://pubmed.ncbi.nlm.nih.gov/35039162/
https://academic.oup.com/eurheartj/article/38/32/2478/3608700