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Divided dose or all at once?

Polymyalgia Rheumatica (PMR) | Last Active: 4 days ago | Replies (17)

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@dadcue

I'm currently off prednisone but I took it for more than 12 years for PMR. I don't think there is a single correct way to take prednisone. I refer to the "depends how I feel" method of tapering. It might also be called the "try it and and see method."

I found that splitting my dose worked well. I took approximately 2/3 of my dose in the morning whenever I woke up. There was no set time for when I woke up except more often than not it was about 2-3 a.m when pain woke me up.

The pain wasn't wasn't always the same. When I didn't wake up at 2-3 am that was a good thing. I slept a good 8 hours and 7-8 a.m. was my wake up time.

I would reserve 1/3 of my dose for the evening. The effects of prednisone did wear off for me too. I needed some in the evening but not half of my dose. Usually 1/3 of my "total dose" for the day was enough but not always. I could take a couple of mg more in the evening if I felt the need. I kept track of my "total dose" for the day.

I didn't adhere to any fixed dose. I tried to be consistent and stay on a "staple dose" each day. I didn't adjust my "total dose" until there was a reason to. If there wasn't any "compelling reason" to take more prednisone, I would take less prednisone. I tried to take the amount that I thought my body needed and that was based on how I felt.

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Replies to "I'm currently off prednisone but I took it for more than 12 years for PMR. I..."

I take mine in the morning. My symptoms were always worse in the am till early afternoon. I had very little pain past early afternoon.

Just be careful taking at night it will mess with some people’s sleep schedule.