I had hot flashes after radiation therapy and during Orgovyx treatment. The hot flashes continued for about 2 months after finishing a 4 month course of Orgovyx treatment then tapered off over the 3rd month. My initial PSA was 5.7 and my most recent (6 months post treatment was .27. The sexual side effects (which could be related to either or both) have not improved at all but I am glad to not have hot flashes any more. Consumerlabs.com mentions the use of soy isoflavones and black cohosh for hot flashes but I have no further knowledge or experience. And this was concerning female menopausal symptoms. The only mention in men was that one study showed an increase in advanced prostate cancer in men with a higher dietary intake of soy isoflavones so that would indicate caution.