My signatera blood test went up to a 5 and they did the cryoablation this last Monday. They froze off a spot that is so small they cannot even get a biopsy but assume it's cancerous. They could not find anything else but will scan again in about 3 weeks. Hopefully my blood tests will come back down from doing this procedure. If not we will take care of whatever shows up. I've done 2 of these cryoablation procedures in the past and they are not too bad. Much better than surgery. So far so good and keeping my fingers crossed. Signatera blood testing seems to do a good job detecting cancer very early instead of latter when it would be much harder to deal with.