Talk to your oncologist about this - I did. She said the surgery reduces like 80% that it will return.. Then the radiation like about 50% of that. So now we are down to (50% of 40 = 20%). Then the anastrozole takes another 50% - so now we are down to a 10% chance of re-occurrence. I hope I didn't over simplify it - but the point is each additional treatment decreases the chances it will return. And if it comes back - it will not likely be Breast cancer, but something much worse. Someone told me I was strong, which I never considered myself to be. In this fight we must all be strong. When side effects happen - we need to try to deal with them & be positive. Trusting your oncologist is very key. Feeling free to discuss these problems with them is important.