many reasons...my teeth all fell out, my hair on one side fell out and continued all over till now it is very thin, I stopped dreaming, 2/3 hours of sleep per night, I felt nothing about anything, no passion, I was like a zombie, I lost interest in things I had always loved, My character started to change to real impatience, anger, irritability...and terrible headaches for days. I lost my imagination which kept me alive (I am an artist and have been working like an automitan.... no inspiration dull and mindless) and was my modus operandi, my profession and ever lasting love, reduced to automatic pilot..My career greatly suffered... I lost a lot of my contacts and friends due to inaction... There are other contraindications which I do not want at all, which I hadnt realised really matter to me also, like Prednisone hinders healing, cancels the adrenal glands (I am working on building my adrenal glands up again and it will take a while, but anything is better than the helplessness I have been experiencing)
These are not life threatening in a physical way but caused me to be utterly depressed about my life to the point of giving up...It took a long time to get down to nil...but I bit the bullitt in February and even tho' the pain has come back tenfold I know what to do and am seriously working on healing myself.