I started this drug only in November 2018. So far I have the dry eyes, but am wondering how I can tell the difference in knee pain from arthritis vs. the side effects of anastrozole. Also feeling tired all the time. Does anyone have any suggestions to the tiredness? I'm 63, Stage 1, HR+, ER+, HER-. I only needed radiation. Also hot flashes have increased. 🙁 Several people mentioned most women stop taking it from the side effects - what is the percentage of these people? I was told 5 to 10 yrs on this. I hope in 5 years they will have more info on whether another 5 years helps or not.