For me the desire to eat got better with Creon treatment. I am now up to 72,000 and my intestinal symptoms are better and my appetite seems to be better. I am trying to take in some high protein drinks. Fairlife seems to taste the best to me. Doesn't seem to be too filling so I still feel like eating at a meal time. Appetite didn't change with the chemo, I have had 11 rounds. I am scheduled for surgery June 21st after going from borderline operable to operable. I am concerned because of my nutritional state. I went from 145 lb to 108. Finally stabilizing after the increases in Creon.