Connect
← Return to Polymyalgia Rheumatica (PMR): Meet others & Share Your Story
Discussion
Polymyalgia Rheumatica (PMR): Meet others & Share Your Story
Polymyalgia Rheumatica (PMR) | Last Active: Nov 18 7:12pm | Replies (1907)Comment receiving replies
wow - i feel startled by your comment re: Actemra. A quick google search re: biologicals for PMR shows the site for KEVZARA and the recent FDA approval "To treat adult patients with polymyalgia rheumatica (PMR) who have had an inadequate response to corticosteroids or who cannot tolerate corticosteroid taper." i am only searching out new literature and reviews about PMR ( post 2018) The Am Coll Rheumatologists ( ARC) guidelines were published in 2015. this title from Feb 2023 is easy to read : "Treat-to-target recommendations in giant cell arteritis and polymyalgia rheumatica". Christian Dejaco - first author. PS>My doctors are at Mass General and that was one of the sites for the clinical trial for Kevzara in PMR>
Replies to "wow - i feel startled by your comment re: Actemra. A quick google search re: biologicals..."
For anyone looking for more conversations on Kevzara, here are a few more discussions:
--- Has anyone heard this news about Kevzara approved for PMR?: https://connect.mayoclinic.org/discussion/has-anyone-heard-this-news-about-kevzara-approved-for-pmr/
--- PMR & Kevzara: https://connect.mayoclinic.org/discussion/pmr-kevzara/
--- Kevzara (sarilumab) to treat PMR: https://connect.mayoclinic.org/discussion/kevzara-sarilumab-to-treat-pmr/
Connect
I take Actemra for the treatment of PMR.
Actemra is FDA approved for the treatment of GCA. My rheumatologist thought Actemra should work for PMR too.
Kevzara was recently approved by the FDA for the treatment of PMR.
Actemra and Kevzara belong to the same classification of medications. They are both IL-6 receptor blockers. The IL-6 inflammation pathway is implicated in both PMR and GCA.