I had same side effect from Arimidex,increased in anxiety and lots of crying. The oncologist referred me to psychiatrist that placed me on anti-anxiety medication to help with symptoms. I was on Arimidex for 5 months prior to surgery. The medication did what it was suppose to, the tumor decreased in size. I stopped taking day prior to surgery and after a a few days the anxiety dropped. I have already told oncologist I do not want to take Arimidex, she suggested we discuss hormone therapy options in 6 months after done with chemo and radiation.