So my palliative staff had me take zofran alternating with phenergan every 4 hours starting hours before treatment started. I took that round the clock for the first 3-4 days. Even set my alarm to take in middle of the night the first two nights. Helped immensely!! Having small dry meals through out also helped me-kind of like with morning sickness. Of course you have to watch for constipation with the nausea meds but that seemed more manageable.

Try rinsing your mouth with baking soda - I prefer that to the Dukes mouthwash they prescribed.