Hi there. I recently had a mastectomy for Estrogen and progesterone positive receptor breast cancer. No chemo or radiation. I am unsure if those factor into the side effects of the anastrozole therapy. My main concern was joint pain. I am very active and did not want the drug to take that from me. A friend suggested I take the drug closer to bedtime or in the evening after my workout and daytime activities. I have to say, it has made a difference for me. The one thing that has REALLY helped me is that I now stretch my legs and hands. Every day without fail. Nothing fancy. There are a lot of great tutorials online. If you live near a yoga studio try restorative yoga. Longer stretching postures, seated or laying down. Not sure about hair loss. I was expecting chemotherapy, so frankly any hair I have is a bonus! Best of luck and God Bless to all of you!