Hi covid stinks,
(Yes, it really, really does stink! I want to use all my bad words here...)
I also have an autoimmune disease, depression and anxiety.
I think the mental health issues derive directly from the difficulties coming from the autoimmune disease.
My rheumatologist treats the AI with medications, and she also prescribed Cymbalta, which seems to be the same route that Grammy 82's doctor took. Grammy 82 is 100% correct about getting a competent doctor! And a good therapist!

Even competent doctors can be stumped by autoimmune diseases. If your symptoms, like mine, don't fit clearly into one of the many categories, then you just have to trust the doctors, keep good records of your symptoms (so that the doctor can know what's going on), and do some research of your own.

Getting a good therapist can take some trying. I got really, really lucky! My current therapist also has a chronic disease and so understands a lot about my anxiety and depression issues. And she has good cognitive behavior therapy tactics to help with the issues.

I think (I'm not sure) that "biologics" is the term used to describe medications that have been developed through human cell research. The ones I know about are Humira and Remicade, which both worked great for me for a few years. I'm pretty sure that the "biologics" have to be given through intravenous infusion or through a self-injected pen. There may be some newer ones that are pills; again, I'm not sure. The biologics that I have been on are very powerful medications with some pretty significant, possible side effects (increased risk of certain cancers).

It took me a few years to decide to take these powerful medications, but I finally reached a point where the disease was so bad that the risk of the medication was worth it for me. The risk-benefit analysis is your decision, with the guidance of your doctor.

Sorry for "a book" in reply! Good luck and keep us posted!