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ANA positive then negative then positive...

Autoimmune Diseases | Last Active: Jul 24, 2023 | Replies (53)

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@wlc222

My situation is very much like yours. I have been told by many it sounds like a Connective Tissue disorder... I had a positive ANA last summer and had additional testing done that didn't reveal much. This month I had a neg. ANA????? but a positive HLA-B27.

These are my symptoms;
3 retinal detachments and scarring from surgery
Uveitis
Hypertrophic Scarring
GI issues -Constipation, Barretts Esophagus and Reflux
Moderate to Severe Raynaud's Disease
Fatigue
Muscular aching and soreness
Circular red rashes on legs, arms and torso...come and go.

Seeing a new Rheumatologist next month. Also, Uveitis specialist. I'm sure I forgot some other symptoms...Help!!!!!

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Replies to "My situation is very much like yours. I have been told by many it sounds like..."

My doctor has referred me again to rheumatologist because the last referral did not work. I have read that once you have a positive ANA you do not need dto keep testing it. I mentioned to my doctor that maybe may Titer is too low to consider and she said I had 2 different patterns. I am happy she is taking it seriously. I am also being referred to genetic testing to see if it might be Ehlers Danlos. Fingers crossed for answers. I hope your new rheumatologist figures this out for you!