I was taking lexapro 10 mgs for half a year without problem. But for a better result to my symptoms the doctor upper it to 20 mgs (bc 10 mgs is not therapeutic) I am misserable with the opposite effect asleep during the day (narcolepsy) and had to stop it completely. The same happened last year when trying with low dose bupropion (75 mg). I am autoinmune and use a biologic. Don’t understand why I get dissable when trying ssri. Before getting the autoinmune diagnosis and treatment, I never had problems with antidepressants in high dosages!!