Hi @tamborazo -- I'm sorry to hear about your friend. That's a pretty large tumor, but men aren't usually watching for one. Since breast cancer is much less common in men, I'm curious if your friend has the BRCA 1 or 2 mutation. If so, about how old is he if I can ask? My son is BRCA2+ and just turned 40 so I'm encouraging him to start his screenings.

I'm hoping you'll get responses from males with BC. I have female MBC (stage 4) with a tumor in the chest wall and pectoral muscle 7 years post mastectomy (2nd time to have BC), but it wasn't in the bone. My tumor was only 1.2 cm, but highly aggressive with Ki67-50%. ER/PR+, HER2- LVI. They removed the tumor and part of the muscle. Positive margin. Then I had 37 radiation treatments. Now I've been on Kisqali and Letrozole for over 2 years and will stay on that course so long as the meds work. I'm currently getting CT scans every 6 months. Treatment may be different for a man based on tumor specifics.

My heart goes out to your friend. Please post info about his second opinion. Thank you!