My endocrinologist put me on Fosamax when I first started out with 80 mg. of Prednisone. He, rightfully, thought that I would not be on the Prednisone forever and I could easily get off of it. He did not want me to take either 6 or 12 months worth of a medication. Well, lo and behold, I am still on the Fosamax after almost 4 years of Prednisone. I am down to 11 mg.