I was staying in bed after my injection but for the last half of treatment I found I handled side effects much better if I got up and out! The wooziness, heart palps etc. were worse when I lay down!! Everyone is different and this is so counterintuitive. But now I inject and start my day- even go to art class right after shot. Not saying that is true for anyone else.....For me the big thing was risk of afib at night- that is why I switched.