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Lupron yeah or Lupron nay that is the question.

Prostate Cancer | Last Active: May 19, 2023 | Replies (70)

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@greglynch7

Stage 4 PCA 20 yrs ago. I’m 70, had radical prostatectomy and PSA recurred in 1 year. Started lupron and worked for most of that time but we all become castrate resistant eventually but lupron has kept me alive. Unfortunately after 18 yrs on lupron I developed coronary disease with no other coronary risk factors. Little was known about the very long term effects of lupron/testosterone depletion therapy.
Lupron has been very effective and not many people have been on lupron this long.
Lupron side effects are there but tolerable and hormone treatment has repeatedly been shown to be the best effective treatment for me. Unfortunately my cancer has become metastatic to many bones and I’ve been through every treatment available ( too long to enlist here) but I attribute my survival to lupron. There is a cost to every treatment. There is no cure for advanced prostate cancer yet but lupron may be the ONLY treatment over 20 years that has done anything.
Keep investigating as WE are our best advocates and make our own decisions based on what we are willing to accept and the information available. The docs are there to give us our options sometimes not great options. Keep hopeful.

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Replies to "Stage 4 PCA 20 yrs ago. I’m 70, had radical prostatectomy and PSA recurred in 1..."

Diagnosed in January stage 4 with PSA over 200 and gleason 8 and 9. Treated with Lupron, Zytica and local radiation as spread was local. Yes, side effects with hot flashes, and urinary issues which could have been caused by the radiation as well. Anyway, psa is now less than one and libido issues and shrunken testicles. I am 64 and would do it again as planning on being around a long time.