← Return to Severe Adrenaline Spikes every morning - please help

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I have this, but I have it continually in a 24 hour period and have had it for five years. I’m now to the point that I’m getting twinges in my heart because too much adrenaline or cortisol is affecting my heart. I don’t just wake up between five and seven AM with that spike, I wake up 10 times a night and then this happens to me all through the day. I average 18 to 28 spikes per day You think you would lose weight with all this adrenaline constantly but it’s just the opposite. I’ve been to three endocrinologist. I’ve had the cortisol levels checked at different times with captured urine, blood tests, and MRIs. Everything is fine.
It’s a medical mystery.

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Replies to "I have this, but I have it continually in a 24 hour period and have had..."

Constant spikes of adrenaline aren't good.
Do you have headaches and excessive sweating too?
These can be symptoms of adrenal gland problems.
Yes it's a horrible feeling,like your body is in constant fear, flight or fright mode.

Until I saw these messages. I thought I was so alone with this problem. Feeling suicidal. Can’t even do the things I used to do. Fear all day never knowing when one will come. I haven’t been to an endocrinologist yet. Do they help you.

@hopscotch I know this is an old post, but I am experiencing the exact same thing and wanted to see if you ever found out what was causing your spikes and how you are feeling now. I’m having to increase my beta blocker dose to deal with this. I do have POTS, but this is worse than it’s ever been. I am thinking it’s perimenopause in my case, and I’m hoping the progesterone cream I just got will start to help soon.

@hopscotch
Hi. It's now 2026 - three years after you posted. I hope you're feeling better. I'm writing because I'm having similar issues, though not as many spikes. Have you gotten to the bottom of this? If so, please share. In the meantime, here's my story, below. Please comment if you have any questions or you can provide any suggestions. Thank you so much!!

I have adrenaline or cortisol attacks every three hours during each and every day, and a couple times during the middle of the night before I wake. I've been dealing with this for 2 1/2 years, and not a single doctor (including several endocrinologists) can tell me what's going on. Does anyone else have this, or know what causes it?

When the attacks first started happening, I'd get frantic, almost like a panic attack - breathing fast, adrenaline surging, anxious, impatient, desperate, etc. Now, knowing the signs when they're coming on, I simply eat a plate full of protein, vegetables and complex carbs and that stops the symptoms fin their tracks, until precisely three hours later, when they come again. Occasionally, get brain fog if the symptoms arrive before I eat, and I can't think straight which is scary. I put my feet higher than my head and rest until I'm better. It's affected my quality of life, needless to say, and I need to have food with me at all times when the symptoms come.

Unfortunately, one endocrinologist insists these are panic attacks and wants me to see a shrink for some CBT. I've got a pituitary adenoma (and have had a few high cortisol tests, which the Dr. says is normal with stress, HRT, etc.). I don't have diabetes, though my a1c is creeping up as all this eating is causing me to gain weight. I've gained 30 lbs over this time.

I'm aware the "food" is the only way ""I"" know of to stop these attacks from causing who-know-what from happening. I don't know what else to do. Feels like I'm gonna die if I don't stop the feelings / attack.

Does anyone have issues like this, or know what this might be?

Thanks so much for your thoughts!