I take one 70 mg Alendronate tablet per week on Sunday. Is it okay to take one 250 mg tablet of Aleve on Tuesday and one 250 mg tablet of Aleve on Thursday ? I always take it with plenty of water and some food in my stomach. It's the only thing that reduces my inflammatory arthritis. I can barely walk or move without taking Aleve. I take as little as possible just so I have 2 or 3 days a week that I'm able to walk a bit and get things done.