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Anyone taken Evenity (romosozumab) for Osteoporosis?
Osteoporosis & Bone Health | Last Active: May 23 12:33pm | Replies (1142)Comment receiving replies
@pedsnurse61 if you do Prolia you will eventually do Reclast or another bisphosphonate anyway because you cannot just stop Prolia without quickly losing what you gained.
In his new book "Great Bones," Dr, Keith McCormick explains that Reclast stays in the system much longer than Prolia, with a very long half life of 10 years, so you can safely take a break from meds once your gains have been "locked in."
You can do Prolia for a few years, but you also, according to the same book, have to be careful about the timing of the switch to Reclast from Prolia. If too soon, the Reclast won't work and if too late, the rebound effect of stopping Prolia could already kick in. He suggests doing CTX tests to determine timing.
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Right- I keep reading about the very long half life of Reclast- that it stays in your body virtually forever.
I read one explanation that as it’s deposited in your bones, the osteoclasts do their thing ( breaking down bone) thus releasing the Reclast.
So I’m wondering why we’re advised to take it every year for 3-5 years???
I also read another study that said a half dose, as well as every 18-24 months is as effective as usual administration.
* I’d post a link but the studies don’t allow it somehow. If interested I can try to post that.