Hi @mir123 -- like you and @callalloo I choose quality over quantity, but to me that means doing what I think I can reasonably tolerate and not live in misery. I declined chemo, but did surgery and radiation. I am currently doing targeted therapy and the side effects are tolerable. I continue to enjoy daily life and focus on short term goals meaning things I want to accomplish in the next year. I do have limited energy so I focus on the things that are most important to me. Prayers for you.