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PSA - 17.1, are Lupron injections necessary?

Prostate Cancer | Last Active: Apr 11 7:23am | Replies (84)

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@spryguy

Ditto on the side effects. Add Zytiga to that and it's even a tougher go.
I've accepted all the downsides and look forward to the cessation of treatment in 10 - 16 mos. . One worry that I have is cognitive decline.
My ability to do crossword puzzles has decreased by a lot. Other signals have also started to flash. The scientific studies (articles) seem to be voicing similar conclusions. Androgen deprivation for 12 mos or more may contribute to non-reversible cognitive loss.
ANDRGREN DEPRIVATION THERAPY IN PATIENTS WITH PROSTATE CANCER.......
2022 Study by Jong Won Kim et al. Published in MENS HEALTH
JULY 2022.

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Thanks for the info. Good luck with all.