All great advice, thanks💞

I too have had numbness in my feet which has changed my walking style. I am constantly monitoring how I walk --much more slowly and carefully. Just recently I've become aware of tingling in my left hand , only at night in bed. It seems to go fairly quickly but I am disturbed by it. I've been on prednisone [from 60mg down to 12.5mg now]since August 22. Also a cocktail the drugs including methotrextate just recently. I had PMR back in 2015/16, then GCA since last August.

Thank-you for the update. Sounds like you are making progress with tapering prednisone.

I developed peripheral neuropathy within a year after PMR was diagnosed. I wasn't diabetic and I'm still not diabetic despite many years of prednisone use.

Don't do what I did in regard to the peripheral neuropathy.. I actually told my primary care doctor that the numbness and tingling in my feet was "the least of my worry because it didn't hurt." I regret saying that because now peripheral neuropathy is diffuse and is affecting my arms and legs. An EMG/NCS should be done but that didn't identify the cause. The neurologist said my peripheral neuropathy was idiopathic.

An endocrinologist shed some light on the subject when my insulin level was found to be very high. The endocrinologist said that even though I wasn't diabetic, I did have insulin resistance. Impaired glucose regulation can lead to peripheral neuropathy. He said prednisone also leads to metabolic syndrome and peripheral neuropathy is a common result. I knew that prednisone wasn't helping my overall health and well being but I didn't fully appreciate everything that prednisone was doing to me.

I'm glad that Actemra seems to be working. Things get really interesting when you get below 10 mg of prednisone. There is the problem with adrenal insufficiency that creeps up on you when you try to reduce too fast after you get below 10 mg. Secondary adrenal insufficiency can only be pinned on prolonged use of prednisone in most cases.