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Thanks, Lisa! I'll check that discussion out. I'm thinking we need to know specifics on my mom's mutation as we haven't been told exactly what her's is. He has shared that it is likely her cancer develops a resistance to this Tagrisso, is that common for all mutations or more likely just for my mom's, do you know?

Thankfully she is physically doing quite well. We discovered her cancer from her suddenly sensing numbness in her lower body and a mysterious bladder issue. After a couple of months of her doctor and some specialists scratching their heads a neurologist at Mayo discovered a lesion in her sacrum that is pressing on the nerves controlling her bladder and lower body, then found the primary in her left lung. She had immediate radiation for 5 days on the sacrul lesion and is starting this TKI Tagrisso tomorrow to tackle the left lung lesion and the mets in her brain. Emotionally, it's a rollercoaster but we're taking things one day at a time.

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Replies to "Thanks, Lisa! I'll check that discussion out. I'm thinking we need to know specifics on my..."

Her oncologist will have more specifics, but generally Tagrisso is prescribed for patients with an EGFR mutation. So far, the various targetable cancers will find a way to mutate around the TKIs, and become resistant. That isn't specific to EGFR or Tagrisso. Those cancer cells are just too smart. There are very smart scientists working their magic in continuing research aimed at delaying or stopping this resistance from happening, and there are always new medications in development too. There is no way to predict who can have long success on the meds. We all need to be thankful for the extra time, and hopefully good quality of life during that time.
I'm glad to hear that she's doing well physically. Dealing with the weight of the diagnosis is very difficult, especially in the beginning. I'm sure it's not easy to watch her go through this, but she's very fortunate to have you at her side.