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Kevzara (sarilumab) to treat PMR

Polymyalgia Rheumatica (PMR) | Last Active: Apr 4 7:55pm | Replies (156)
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@southtexas

Has anyone been on Kevzara for more than a couple of months? Would really be helpful to know how it worked for you. I took my first dose but still am apprehensive.

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Replies to "Has anyone been on Kevzara for more than a couple of months? Would really be helpful..."
redboat | @redboat | Jul 14, 2023

How is it going with Kevzara?

I am self-injecting weekly with Actemra, which is also a "biologic" with a similar effect - it also an IL-6 inhibitor. Actemra has been very effective in reducing my PMR/GCA symptoms as I taper off Prednisone (now at 7.5 mg/day, down from 60 mg/day, and slowly going lower). The only side effect I have noticed is a slight increase in my ALT liver score, but it is still well within normal range at 20 U/L . Kaiser says anything below 47 U/L is normal. My past scores have been around 13 U/L when I was completely healthy.

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